CELL GRAND CLINIC is a leading advanced regenerative medicine clinic in Japan, specializing in science-based, personalized stem cell and cellular therapies. Certified by Japan’s Ministry of Health across 13 specialized regenerative treatments, the clinic focuses on restoring function, slowing biological aging, and improving quality of life through cutting-edge medical innovation.

The clinic exclusively utilizes autologous therapies and premium cell cultivation protocols, ensuring maximum safety, transparency, and therapeutic effectiveness. CELL GRAND CLINIC treats both chronic and age-related conditions by targeting root causes rather than symptoms.
Medical Philosophy
CELL GRAND CLINIC believes in harnessing the power of a patient’s own cells to activate the body’s natural healing mechanisms. Regenerative medicine is used as an alternative or complement to conventional drugs and surgery, minimizing systemic burden while supporting long-term recovery and vitality.
Quality control is central to every treatment. All cells are carefully cultivated under strict safety standards, with no pre-batching and full sterility testing, reflecting Japan’s highest medical quality benchmarks.
Key Treatments & Services
Stem Cell & Regenerative Therapies
- Autologous Adipose-Derived Stem Cell Therapy
- Stem Cell Culture Supernatant (Exosome Therapy)
- Fibroblast Therapy
- Platelet-Rich Plasma (PRP) Therapy
- NK / NKT Cell-Based Immunotherapy
Condition-Specific Treatments
- Chronic Pain
- Knee Osteoarthritis & Joint Disorders
- Diabetes & Prediabetes
- Arteriosclerosis
- Age-Related Frailty & Vitality Decline
- Hair Loss (AGA / FAGA)
- Erectile Dysfunction (ED)
- Skin Aging & Dermal Regeneration
Longevity & Preventive Medicine
- NMN Longevity Therapy (nanoPDS® technology)
- Comprehensive Blood Screening
- Ultra-Early Cancer Screening (Exosome-Based)
- Genetic Aging Assessment (EpiClock Test)
Ministry of Health–Certified Regenerative Treatment Plans
CELL GRAND CLINIC operates under officially approved regenerative medicine plans, including:
- Chronic Pain Treatment – Type 2
- Osteoarthritis & Joint Disorders – Type 2
- Diabetes & Prediabetes – Type 2
- Arteriosclerosis – Type 2
- Frailty & Pre-Frailty – Type 2
- Androgenetic Alopecia – Type 2
- Erectile Dysfunction – Type 2
- Knee Joint PRP Therapy – Type 2
- Dermal Fibroblast Regeneration – Type 2
- Skin Rejuvenation (Stem Cells) – Type 2
- Skin & Hair PRP Regeneration – Type 3
- Cancer Prevention (NK Cell Therapy) – Type 3
Medical Director
Yuichi Wakabayashi, M.D., Ph.D.
Medical Director – CELL GRAND CLINIC
Credentials & Expertise
- Board-Certified, American Board of Regenerative Medicine
- Board-Certified, Japan Society of Anti-Aging Medicine
- Board-Certified Diagnostic Radiologist
- Board-Certified Nuclear Medicine Physician
- NIH Research Fellow & University Lecturer
Dr. Wakabayashi is internationally recognized for his contributions to regenerative medicine, neuroscience, and molecular imaging. His research has been published in leading U.S. and international medical journals, and he is the author of multiple Amazon #1 bestselling medical books.
Academic & Research Excellence
- Published in Journal of Nuclear Medicine, ACS Chemical Neuroscience, Neurological Sciences, and more
- First-author and co-first-author on pioneering PET imaging and regenerative research
- Featured in The Wall Street Journal for innovative patient-centered care
- Recognized globally for advancing cellular and regenerative therapies
Why Choose CELL GRAND CLINIC?
- Ministry of Health–certified regenerative treatments
- Japan-grade safety, sterility, and quality standards
- Personalized, science-driven treatment protocols
- International patient-friendly care with English support
- Focus on longevity, vitality, and long-term health
International Patient Information
CELL GRAND CLINIC welcomes international patients seeking advanced stem cell and regenerative medicine treatments in Japan. The clinic provides English and Chinese language support, ensuring smooth communication throughout consultation, treatment planning, and follow-up care.
International patients receive personalized treatment programs based on medical history, diagnostic results, and individual health goals. Online consultations and pre-arrival coordination are available to help patients prepare before traveling to Japan. The clinic follows strict Japanese Ministry of Health regulations, offering one of the highest safety and quality standards globally.
Located in central Osaka, CELL GRAND CLINIC is easily accessible from international airports, hotels, and major transportation hubs, making it a convenient destination for medical travelers seeking premium regenerative care.
Treatment Comparison Table
| Treatment Type | Primary Purpose | Key Benefits | Cell Source |
|---|---|---|---|
| Autologous Adipose-Derived Stem Cell Therapy | Regeneration & disease repair | Reduces inflammation, restores tissue, improves function | Patient’s own adipose tissue |
| Stem Cell Culture Supernatant (Exosome Therapy) | Cellular signaling & rejuvenation | Non-cell therapy, faster recovery, high bioactivity | Cultured stem cell derivatives |
| PRP (Platelet-Rich Plasma) Therapy | Healing & regeneration | Enhances tissue repair using growth factors | Patient’s own blood |
| Fibroblast Therapy | Skin regeneration | Improves elasticity, collagen production, skin quality | Autologous dermal fibroblasts |
| NK / NKT Cell Immunotherapy | Immune enhancement & cancer prevention | Targets abnormal cells, boosts immune defense | Patient-derived immune cells |
| NMN Longevity Therapy | Anti-aging & metabolic support | Activates sirtuin genes, improves mitochondrial function | Pharmaceutical-grade NMN |
Cost Disclaimer
Treatment costs at CELL GRAND CLINIC vary depending on the type of regenerative therapy, medical indication, number of sessions required, and individual patient health condition. Final pricing is determined after a detailed medical evaluation and consultation with the clinical team.
All regenerative treatments are personalized medical procedures, and prices may differ from standard estimates. Travel expenses, accommodation, and non-medical services are not included unless explicitly stated. Patients are encouraged to request a customized treatment plan and cost overview prior to scheduling their visit.
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